Regulatory Toxicology and Pharmacology

The difference between hazard and risk. Ensuring the safety of fragrances is a priority for both consumers and industry.

4-MBC Banned in EU

Due to concerns about endocrine disruption, this material has, as of 1 May 2026, been banned in the EU and will be banned by the UK in January 2027. It is also currently under review by the TGA. READ MORE.

NZ Cosmetic Products Group Standard Changes

Changes to New Zealand Cosmetic Products Group Standard

Bemotrizinol gains FDA approval

On 9 June 2026, the US FDA approved this UV active for use in sunscreen formulations at a maximum permitted level of 6% w/w. READ MORE.

The difference between hazard and risk: the dose range prevalent in toxicological studies vs real life fragrance exposure

Kaushal Joshi: Research Institute for Fragrance Materials, Mahwah, NJ, United States of America
Arianna Bartlett: Research Institute for Fragrance Materials, Mahwah, NJ, United States of America
Wolfgang Dekant: University of Wuerzburg, Department of Toxicology, Würzburg, Germany
I. Glenn Sipes: University of Arizona, College of Medicine, Department of Pharmacology, Tucson, AZ, United States of America
Gerhard Eisenbrand: Food Chemistry & Toxicology, RPTU Kaiserslautern-Landau, Kühler Grund 48/1, Heidelberg, Germany

Regulatory Toxicology and Pharmacology

Regulatory Toxicology and Pharmacology

Table of Contents

4-MBC Banned in EU

NZ Cosmetic Products Group Standard Changes

Bemotrizinol gains FDA approval

The difference between hazard and risk: the dose range prevalent in toxicological studies vs real life fragrance exposure